A case of agranulocytic angina, which took a acute course after taking one bottle of “Panpyrin solution” ※for her common cold, was reported. Patient is a 17 years old female who was apparently healthy until 3 days prior to the admission when she developed a severe sorethroat with bleeding from oral cavity and progressive general malaise. Patient died on the 8th day of her hospitalization. On her admission, the blood and bone marrow studies revealed as follows ; Blood : R.B.C. 1,770,000, Hb 5.8, W.B.C. 2100, Seg. neut. 2%, Stab. neut. 0%, Lymphocyte 87%, Eosinophile 0%, Basophile 0%, Monocyte 11%, Bone marrow ; Stab. neut. 5%, Seg. neut. 3.5%, Lympho. 37%, Mono. 0%, Eosino. 0%, Baso. 0%, Myeloblast. 0.5%, Promyeloblast. 4%, Myelocyte. 9%, Metamyelocyte. 15%, Plasma cells. 1%, Basophilic normoblast 1%, Polychromatophilic normoblast. 13%, Orthochromatophilic normoblast. 11%. ※ Panpyrin is the name of tread-mark which contain of 250mg of sulpyrin, 150mg of aminopyrin, 50mg of caffein, 100mg of taurine, 50mg of Vitamin C, 30mg of becantex, 25mg of dl-methyl ephedrine HCI in 20cc bottle.